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has gloss | eng: The c-myc internal ribosome entry site (IRES) is an RNA element present in the 5 UTR of the mRNA of C-myc and allows cap-independent translation. The mammalian c-myc gene is a proto-oncogene which is required for cell proliferation, transformation and death. c-myc mRNA has an alternative method of translation via internal ribosome entry where ribosomes are recruited to the IRES located in the 5 UTR thus bypassing the typical eukaryotic cap-dependent translation pathway. |
lexicalization | eng: c-myc internal ribosome entry site |
instance of | c/Cis-regulatory RNA elements |
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